BPC-157 is a synthetic pentadecapeptide derived from a protective protein fragment originally isolated from human gastric juice
Not FDA approved
In a second step, glutathione synthase (GshB) adds a glycine to the C-terminus of this dipeptide, resulting in -glutamyl-cysteinyl-glycine (glutathione) (Apontoweil and Berends, 1975
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In contrast, for those diseases caused by NRF2 loss of function or a defect in one of the NRF2-regulated pathways, reactivating an alternative pathway that could also contribute to ROS detoxification might be a way to resolve the problem