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In many cases, definitive treatment of gallbladder disease (such as laparoscopic cholecystectomy) allows patients to safely continue GLP-1 medication if clinically indicated

That is roughly double what semaglutide achieves at its highest approved dose

Over time, the pancreas may struggle to keep up with the heightened demand for insulin, causing further elevation of blood sugar levels

Another analysis also found that while there is some evidence of a slight increase in pancreatitis cases, the overall risk remains very low

Monitor for any unexpected effects

The chart below shows just how neatly rising GGT levels correlate with increased health risks, which really drives home why you should aim for the optimal range for a longer life