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Clinicians should guide their patients through the benefits and limitations of each to ensure safe and informed decisions

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If additional validation of acetylcarnitine is carried out in a follow-up study, taking into account the larger sample size, controlled subject variables, antidepressant type, and heterogeneity due to pharmacomechanism, the potential of acetylcarnitine as a biomarker for diagnosing depression and remission status will be further elucidated

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Also, Nikolaidis et al

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Factors that influence optimal maintenance dose include starting body composition, individual metabolic response, side effect tolerance, and research goals

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