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91.9% achieved 5% weight loss vs 31.5% placebo

Some studies have highlighted cancer concerns related to specific types of peptide therapies

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Potential adverse effects, such as gastrointestinal issues and long-term safety concerns, also limit widespread adoption

Why Cagrilintide Can Affect Appetite and Digestion Cagrilintide works through the amylin pathway, which is different from the GLP-1 pathway

(A few other, less-invested experts from the FDA were added to the panel after pushback before last weeks meeting