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Role of GLP-1 agonists in managing comorbidities in HFpEF Beyond their cardioprotective properties, GLP-1 receptor agonists exert a beneficial impact on HFpEF by influencing other organ systems and mitigating comorbid conditions that contribute to its progression, including metabolic dysfunction-associated steatotic liver disease (MASLD), chronic kidney disease, and pulmonary disorders

GLP-1 is also cleared relatively quickly by renal filtration [16]

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glp1Trt Stacking Metabolic Health | LiveForeverHealth