The Benoist et al
Despite its therapeutic efficacy, tacrolimus has a narrow therapeutic window (520 ng/mL whole blood 1012 h post-dose) and frequently displays episodes of toxicity, such as nephrotoxicity, neurotoxicity, and glucose intolerance (Chow et al., 1997)
O'Mahoney LL, Matu J, Price OJ, et al
Take off the walker by undoing the straps and opening the inside part
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For some patients, one medication may be more appropriate than the other depending on their health history, treatment goals, and how their body responds to therapy