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All aforementioned systems are important in regulating emotions, impulsive behaviors and reward pathways [25]
MOTS-c has improved glucose uptake into skeletal muscle in animal models
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In an 8-week study using low-dose liraglutide (0.6 mg/day) in patients with type 2 diabetes no weight or fat loss was produced, but both fasting and postprandial glucose were substantially reduced, but neither fasting nor postprandial insulin (or C-peptide) response was increased [19]
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