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seek medical review if bruising is severe, recurrent, or accompanied by unusual bleeding elsewhere

We monitor labs at 3 and 6 months after starting, then annually

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Typical Escalation Schedule : Days 130: 3 mg daily (start dose) Days 3160: Escalate to 7 mg daily , if tolerated Day 61 onward: Possible increase to 14 mg daily , based on clinical response A missed dose should not be doubled