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They form when the injection is administered too quickly and the solution pools rather than dispersing

Multiparameter characterization of cell population of FAB L3 (Burkitt like) leukemia

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RealThiol AM Ester (RT-AM) Glutathione (GSH) Probe RealThiol AM ester (RT-AM) provides ratiometric fluorescent readout for quantification of GSH in live mammalian cells

If the hepatic metabolism is compromised, a downregulation of cytochrome P450 (CYP) enzymes activity can lead to an accumulation of nephrotoxic drugs in the systemic circulation, resulting in kidney injury (Lane et al