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The side effects we occasionally see in clinic are mild and typically transient

The clinical trial tested 12 weeks

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However, this comes with significant caveats

Undetected vitamin B12 deficiency due to false normal assay ...ncbi.nlm.nih.gov articles PMC3827408 by E Scarpa 2013 Cited by 25 Although measurement of vitamin B12 levels is the gold standard for the diagnosis of B12 deficiency some reports do exist concerning difficulties in its assay