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2 T2DM causes changes in cognitive function 2.1 Cognitive impairment in T2DM: stages and risk factors In individuals with T2DM, cognitive functioning undergoes distinct stages of impairment, ranging from diabetes-associated cognitive decrements to MCI and dementia (Tamura et al., 2017)
Research reports that some of these flavonoids can block a protein called organic anion transporter polypeptide (OATP)
More recently, tirzepatide (Mounjaro), approved in 2022, expanded the therapeutic concept further by combining GLP-1 activity with glucose-dependent insulinotropic polypeptide (GIP) receptor agonism
The goal is not maximum mass gain but rather maintaining an anabolic environment during caloric deficit
