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An underactive thyroid gland (hypothyroidism) typically leads to weight gain, fatigue, and other conditions that affect quality of life
Lang E, Lang F
Since peptides are naturally produced by the body and designed to act with precision, they are typically well-tolerated and associated with minimal side effects
Early experimental data raised concerns of a possible risk of medullary thyroid carcinoma, whereas data from randomized trials suggest a possible increase in risk of non-medullary thyroid carcinoma
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Interestingly, Sitagliptin was able to reduce TC cell migration by influencing the expression of some markers of the epithelial-to-mesenchimal-transition (EMT) which ultimately drives cancer cell migration (Hu et al., 2021)
