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How Do These Medications Help With Weight Loss

It is an expanding toolkit

Retatrutide is a weight loss drug that has not yet received approval from the U.S

It engages both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors, which play roles in insulin signaling, blood-sugar regulation, and post-meal satiety pathways

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According to the UK SmPC, no dose adjustment is required in renal impairment (including severe impairment or end-stage renal disease)