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It's a pentapeptide ghrelin mimetic that selectively binds to ghrelin receptors (growth hormone secretagogue receptors, or GHS-R1a) on pituitary somatotrophs and in the hypothalamus

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Reviewed by Written by Published Read Time 89 minutes Published Read Time 89 minutes What Happened The Announcement Explained What Happened The Announcement Explained For the millions of patients who relied on physician-prescribed peptide therapies and the clinicians who prescribed them 2023 was a hard year

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The fact that both cagrilintide and semaglutide have ~7-day half-lives is what makes CagriSema possible as a single weekly research protocol