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This seems obvious, but your muscles allow you to stand, sit up straight , move, lift , and do everything that you do each day

Later, selective inhibitors of thrombin (factor IIa), such as bivalirudin and argatroban, emerged, which were also parenterally administered

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Given the expansion of the AR cistrome and the emergence of novel AR binding sites under ADT, similar to observations during carcinogenesis, it is tempting to speculate that other factors acting at or near AREs may be in play in CRPC