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Severe vitamin B12 deficiency affects about 3 percent of adults in developed countries, but a more marginal deficiency may impact 26 percent, with the highest rates among adults older than 60
Reported effects Supports research into collagen-related signaling and extracellular-matrix remodeling
Documentation helps clinical assessment
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2009 in British Journal of Dermatology : a double-blind randomized controlled trial of a cosmetic anti-ageing product in photoaged skin, which showed measurable improvements in fine wrinkles, mottled pigmentation, and roughness 10
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