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53 It is important to note that the virus can cause both an increase in oxidative stress (and therefore inflammation), as well as mitochondrial dysfunction which can lead to a loss of proteostasis and increase in endoplasmic reticulum stress
Consequently, meticulous monitoring needs become essential
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This is often the first and only sign of gradual degradation that isn't visually apparent
In particular, the drugs can boost insulin sensitivity (in part by slowing the passage of food in the GI tract) and act on parts of the brain that influence appetite and cravings, all of which can reduce that never-quite-full feeling common in folks with PCOS
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