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Animal experimental evidence Osteoclast precursor (RAW264.7) experiment: AOD 9604 significantly inhibited RANKL induced osteoclast formation, reduced the number of TRAP positive multinucleated cells, and decreased bone resorption pit formation
It should be clear and colorless to slightly yellow
The dose is then increased in 2.5 mg increments every 4 weeks as tolerated, with typical maintenance doses ranging from 5 mg to 15 mg
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No human trial has tested the best time, however
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