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GI side effects significantly impact how people manage their daily treatment

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Researchers should ensure they can maintain protocols through completion rather than abandoning research mid-protocol

Altered CAMKII expression, which regulates orexigenic neuropeptides like NPY, also reflected compensatory adaptation to weight loss (Sanchez-Garrido et al., 2024)

Timing: First thing in the morning, before any food, drink, or other medications

Colocalization analyses have pinpointed genetically correlated loci harboring putatively shared causal variants for both MDD and T2DM [57]