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Such GPX4-independent surveillance pathways are often mediated by enzymes that generate metabolites with radical-trapping antioxidant (RTA) activity, including ferroptosis suppressor protein 1 (FSP1), dihydroorotate dehydrogenase (DHODH), and GTP cyclohydrolase-1 (GCH1), etc 10,14,15,16

5 Buttermilk Buttermilk is often used in the food industry and as animal feed

The -glutamyl cycle, first proposed in 1970, contains enzymes that depend on both -glutamylcysteine synthetase (GCL) and glutathione synthetase (GSS), as well as -glutamyl transferases (GGTs) for the entire process of GSH biosynthesis and degradation, respectively [16]

VITATOPS Trial Study Group

Updated database entry

Significance of glutathione in lung disease and implications for therapy