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d-allulose with a rise in portal GLP-1 concentration to a level approximately twofold higher compared to standard chow-fed mice (Fig
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Retrieved from Blachier, F., Andriamihaja, M., Larraufie, P., et al (2021)
usual onset between 3050 years Pathophysiology: Dysregulated immune response autoantibody formation (RF, Anti-CCP) cytokine release (TNF-, IL-1, IL-6) pannus formation cartilage and bone destruction Risk factors: Genetic predisposition (HLA-DR4), female sex, smoking, obesity, and hormonal influences From a medical laboratory perspective, early detection using Rheumatoid Factor (RF) and Anti-CCP antibodies, along with inflammatory markers like ESR and CRP, plays a crucial role in diagnosis and disease monitoring