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At 80 weeks, all doses of retatrutide (4 mg, 9 mg, and 12 mg) met the primary and key secondary endpoints for obesity, delivering clinically meaningful weight loss
They also allow space to be created to implement mindful eating habits and help create different relationships with food
They would still not be FDA-approved medications, and clinical use should continue to be guided by the best available evidence, physician judgment, and informed patient consent
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Uterine fibroids range in size from one tiny speck to several bulky masses
Given that GLP-1s carry a black box warning for thyroid tumors and additional warnings for pancreatitis and kidney problems, the lack of consistent baseline labs feels risky
