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GSH depletion dysregulates the spatial control of neutrophil ROS production, converting a targeted defence into indiscriminate inflammatory tissue damage
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more than once daily), and lasted at least 30 days
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advanced protocols may reach 1520 mg/day under supervision
The requirements of potential nanocarriers for CNS drug delivery are biodegradability, non-toxic characteristics, scalable synthesis and controlled loading or coupling with hydrophilic or hydrophobic drugs [20, 21]
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