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Aside from providing cysteine as a glutathione precursor, NAC also appears to have antioxidant properties by itself, and is a valuable sulfur donor for various metabolic needs

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There was no change in Thymine-DNA glycosylase (Tdg) mRNA level

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That is a folded globular protein with a defined tertiary structure, not a flexible short chain that happens to adopt a helix at a receptor interface