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Most individuals were female (~74%) and non-Hispanic White (~53%)
The reason is that intravenous administration carries a risk of immunogenicity the immune system recognizes Serratiaderived molecular signatures on the enzyme as foreign, which can trigger immune reactions
2011 Sep 15;2011:493462
Dosage: some low-cost providers dilute the solution, so you may be paying mostly for saline
Skin reactions are common (affecting 35-50% of users), including rashes, burns, and blisters
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