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This is an important health benefit because every function of your body, from digesting your food to a shift in your mood, has the potential to produce metabolic waste, generate free radicals and produce a molecular state of imbalance called oxidative stress

+-More strikingly, the findings suggest that GPX4 plays a crucial role in preserving intestinal homeostasis by protecting against lipid peroxidation, as evidenced by the increased vulnerability of IEC Gpx4 mice to DSS-induced colonic inflammation relative to their wild-type counterparts (65)

GR, glutathione reductase

Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia

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Enzymes of the GSH peroxidases family catalyze (facilitate) these reactions