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days First visible results appear within two weeks

4 Seven additional Phase 3 trials are evaluating retatrutide for obesity without osteoarthritis, type 2 diabetes, obstructive sleep apnea, chronic low back pain, liver disease, and cardiovascular outcomes

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Ultimately, the decision between simultaneous initiation and sequential add-on therapy should be individualized, considering patient-specific factors such as comorbidities, baseline kidney function, and treatment goals