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Korkmaz OT, Ay H, Aytan N et al (2019) Vasoactive intestinal peptide decreases -amyloid accumulation and prevents brain atrophy in the 5xFAD mouse model of Alzheimers disease

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The GRADE assessment showed moderate certainty of evidence for the increase in serum vitamin B12 levels and low certainty of evidence for homocysteine reduction, both across all studies and within RCT-only and observational-only subgroups