Slower gastric motility causes retention of food and secretions in the stomach, increasing visceral sensory signaling that feels like fullness or queasiness, while central receptor activation can alter nausea thresholds
Lynfield, Y.L
GLP-1 receptors have been found on spinal cord microglia, which are the brain and spinal cords immune cells, and activation of those receptors appears to shift microglia from a pro-inflammatory M1 state to an anti-inflammatory M2 state [2, 16]
Examples of drugs that are in the latter class include the anti-malarial drugs dapsone and primaquine, as well as rasburicase which is normally used in the treatment tumor lysis syndrome in patients undergoing chemotherapy for hematologic cancers, but has also been used to reduce the hyperuricemia associated with gout
Psychiatry 93 , 11371139 (2022)
Incorporate foods like broccoli, cauliflower, Brussels sprouts, garlic, and kale into your diet to support natural synthesis