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The crop yield component and productivity significantly declined due to Pb toxicity in different rice genotypes [21], where yield reduction was 46.27% to 69.12%
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The 8 mg dose achieved 18.9% weight loss, and the 4 mg dose achieved 16.4% weight loss
Therefore, the combined use of GLP-1 RAs with therapies targeting intrahepatic pathways, such as thyroid hormone receptor (THR-) agonists, fibroblast growth factor-21 (FGF21) analogues, and peroxisome proliferator-activated receptor (PPAR) agonists, presents a promising approach for MASH treatment
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