SIRT1 may reduce NET formation by deacetylating FOXO1 and increasing the expression of the pro-apoptotic protein Bim, which destabilizes mitochondrial membranes by interacting with anti-apoptotic members of the Bcl-2 family and shortens neutrophil survival, limiting their accumulation in liver tissue
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Eating smaller, frequent meals instead of three large ones reduces the volume of food entering your already-slowed stomach
Identifying these triggers can help you manage symptoms without needing to stop your medication
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