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Mandula JK, Chang S, Mohamed E, et al
- Reduces cellular melanin production
This addresses the profound, systemic energy deficits seen in ME/CFS and Long COVID at the root molecular level, potentially lifting the heavy blanket of exhaustion that patients experience daily
Phase 2 (NEJM 2023): 24.2% mean weight reduction at 48 weeks (12mg dose)
It represents what actually happened in the real study population
23 Pigmented BCCs also occur, sometimes presenting as potential melanomas
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