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Yu, W., He, X., Vanommeslaeghe, K
This flexibility helps manage the purging process
Inhibition of GPx4 can lead to an increase in ROS whereas increased GPx4 expression can lead to a decrease in ROS content, and GPx4 performs this function dependent on GSH (37), which is an important component of the bodys endogenous antioxidant system, and is derived from glutamate, glycine, and cysteine by dehydration condensation, and its intracellular level is affected by the ability of SLC7A11 to transporter cystine (38)
1948 Sep;33(9):1123-32
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