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Compared to traditional addiction treatments, GLP-1RAs offer a novel mechanism by targeting metabolic and neuroendocrine pathways rather than direct neurotransmitter modulation

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The drug is also used as an immunosuppressant in kidney or liver transplantation, and requires dosage adjustments in patients with hepatic impairment or with certain drug interactions-5-10-11

The authors compared glycogen levels in the control group, SLC7A11-KO dendritic cells, and wild-type dendritic cells before and after erastin treatment

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[11-13] When it comes to these mechanisms, we have to bring up the study where berberine outperformed common antidiabetic drug metformin -- with fewer side effects