Currently, approximately 422 million people worldwide are struggling with diabetes ( + levels, further diminishing sirtuin activity and exacerbating mitochondrial dysfunction ( Hyperglycemia and IR are responsible for worsening S aggregation and mitochondrial dysfunction, both of which contribute to the loss of dopamine-producing neurons
Gu G, Roland B, Tomaselli K, Dolman CS, Lowe C, Heilig JS (2013) Glucagon-like peptide-1 in the rat brain: distribution of expression and functional implication
Pharmacokinetic modeling suggests that heavier patients may have slightly lower peak concentrations, but the FDA-approved dosing regimen does not require weight-based adjustments
In microdosed form, this translates to smoother glucose curves : fewer midafternoon crashes, steadier focus, and a calmer mood
Choudhery MS, Badowski M, Muise A, Pierce J, Harris DT
Effects of diet and antihyperglycemic drugs on erectile dysfunction: A systematic review 3