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In the malignant phenotype of TCC of the bladder, upregulation of various GST classes occurs
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Due to the lack of unpaired electrons, H 2 O 2 is not a free radical but a potent oxidant that can oxidize mitochondrial components (proteins, lipids, DNA)
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Studies document effects on approximately 31.2% of human genes, representing over 4,000 genes with expression changes of 50% or greater
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