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The mechanical force of water hitting the powder creates localized turbulence that disrupts hydrogen bonds holding the protein structure intact
The most common reported effects are mild injection site irritation and rare hormonal fluctuations
Disclosures reported by authors are available here
References 1 AbbateA.ToldoS.MarchettiC.KronJ.Van TassellB
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In April 2014, Lilly acquired Switzerland-based Novartis AG's animal health business for $5.4 billion in cash to strengthen and diversify its Elanco unit
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