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Masson staining analysis indicated that control mice had significant hepatic fibrosis compared to mice with GSTM2 overexpression (Supplementary Fig
Ranucci, M
As a side note, it may be of interest that while the hunger hormone ghrelin appears to counteract (or rather override) the effects of GLP-1 on satiety, the commonly used anti-diabetic drug metformin appears to increase expression of GLP-1 receptors and enhance GLP-1 secretion and sensitivity in both rodents and humans
This stems from safety concerns regarding potential side effects, particularly gastrointestinal issues such as nausea and vomiting
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