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Finally, setmelanotide can be used in older adults with monogenic obesity, caused by mutations in the leptin signalling pathway, although this is more commonly initiated in children and younger adults with severe and complex obesity [122]

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While weight loss has been linked to improving metabolic activity and heart pumping, as heart tissue and the walls of the blood vessels get thinner, and levels of cholesterol and triglyceride levels are known to become more stable, Novo Nordisk has claimed that Wegovys heart health benefits go beyond the effects of weight loss, at the American Heart Association (AHA) Scientific Sessions in the U.S., that took place in November