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The problem surfaced in clinical trials run in 1992 by Mojsov and David Nathan, a physician and expert in type 2 diabetes at MGH, and those of Holst and Nauck (Molteni, Chen)
Weekly dosing also makes it easier for many users
Top-line data is expected in mid-2028
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Semaglutide manufacturers recommend an eight-week washout before conception, while tirzepatide guidelines suggest four weeks to two months
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