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They block specific cytokines (TNF-alpha, IL-17, IL-23) with high precision
If aggregation remains unresolved, alternative structural techniques such as solid-state NMR or cryo-electron microscopy may be necessary
In terms of adverse drug reactions, aggregated data from phase II and III studies indicate that while dotinurad can potentially cause liver-related adverse reactions, such as hepatic steatosis and abnormal liver function tests, which the incidence is lower compared to benzbromarone
About this article Cite this article Dar, N.J., John, U., Bano, N
The guidelines support the medication classs positive effects of slowing the progression of chronic kidney disease though the effects are likely not as strong as SGLT2i, another class of diabetes medications [39, 40]
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