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Transaminitis is the laboratory signature of hepatocyte injury: alanine aminotransferase (ALT) and aspartate aminotransferase (AST), enzymes that normally live inside liver cells, spill into circulation when those cells are damaged or dying

Supportive strategies such as diet-based interventions and microbiota-focused approaches may therefore enhance outcomes

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Medications such as Semaglutide and Tirzepatide mimic this hormones activity, signaling the brain to reduce hunger and slow gastric emptying, leading to improved portion control and sustained weight loss

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