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Daily high doses of B12 may not likely cause harm in most people, but extremely high doses should possibly be avoided unless a healthcare professional prescribes it

Although the findings support evidence of 5:2 MR as an effective initial lifestyle intervention for those with obesity or overweight and early diabetes, Guo and colleagues said they were unable to determine whether glycemic improvement was due to weight loss or the diet itself, requiring further investigation.

The market is valued at USD 1.94 billion in 2026