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Well, people do seem to react differently
The metabolism and elimination of NAD+ (and its by-products) could be altered in advanced hepatic or renal dysfunction, and high-dose NAD+ might theoretically affect cardiovascular dynamics, so practitioners generally avoid or closely supervise NAD+ use in such settings
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When you come off, you're not fighting metabolic adaptation as severely
Tailoring the dose to each patients needs is important
Heres a general guideline: 1
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