It is well-known as the mother of all detoxifiers
The human gene encodes for two isoforms of the enzyme, namely PEMT1, which is localized in the endoplasmic reticulum and generating most of the PEMT activity, and PEMT2, a liver specific isoform exclusively localized in mitochondriaassociated membranes (Tessitore et al., 2003)
Eur.J Clin.Nutr
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Pharmacol., Vol