This is the same hormone targeted by GLP-1 drugs
Research shows that patients who establish at least three concrete behavioral anchorssuch as logging meals, strength training 3 weekly, and eating 2530g protein per breakfastmaintain 60% of their weight loss two years after stopping medication
It can cause some side effects including stomach upset, nausea, vomiting, dry mouth, headache, and restlessness
In this regard, a role for lipolysis in adipose tissue macrophages recruitment and accumulation has been demonstrated in DIO mice with calorie restriction 51 and, more importantly, the above-mentioned study shows synchronized temporal changes between the peaks in plasma FFAs and macrophage number in eWAT, an effect suppressed in global Atgl / mice
Disc electrophoresis
doi: 10.1016/j.jtemb.2018.12.010 133 ChenJSunDCuiHRaoCLiLGuoSet al