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According to primary trials in T2DM, tirzepatide significantly reduces clinical outcomes like body weight, glycated hemoglobin (HbA1c), lipid profiles, and glucose-adjusted glucagon secretion compared to typical glucagon-like peptide1 receptor agonists (GLP1RAs) [1, 2]

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304 Studies have shown that hordenine decreases the expression of proinflammatory cytokines by suppressing the S1P/S1PR1/STAT3 pathway and promotes the healing of colonic ulcers by regulating the expression of tight junction proteins, including occludin and ZO-1

All the three doses of TZP confirmed an important decrease in HbA 1c and BW