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The enhanced antiporter activity in cell lines from hypertensive patients was not accompanied by a corresponding increase in steady-state NHE-1 mRNA transcript levels, which argues against overexpression of antiporter protein in hypertension
Additional experimental models incorporating glucose tolerance testing and fasting biomarker analysis show no significant changes in plasma glucose or insulin levels following exposure to AOD 9604
2021, pp
Some of those include metformin which is used in type 2 diabetes, heartburn medications that alter the production of stomach acid such as PPIs or H2 blockers, and oral contraceptives
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