Due to its low HP pool of 120, several meta threats can still one-shot Greninja, such as Giratina Ex or Solgaleo Ex, so it's not always roses
Also, make sure you play A Legendary Ocean first so you can use priority if you hit Daedalus off Reasoning or Monster Gate
Sure the older cards that we all know are iconic as hell, but non biased people can find them more boring than sugimori copy-paste stock
Some effects will dispose of others in some form so pretty much we stay with the same number of cards, while others will require certain setups or negative effects the more effective are
At the start of the Damage Step, if this card attacks a face-down Defense Position monster: Destroy that face-down monster
Finally, in terms of threats, Phlage, Titan of Fire's Fury and Ragavan, Nimble Pilferer are the most played by the raw number of copies in all the decklists I analyzed