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If you discarded them from your hand, you could activate their effects, which basically allowed you to do stuff like destroy cards on the field or summon a monster from the graveyard

Take charge with Pikachu & Zekrom-GX

All three cards have ties to Drizzt in some way

Magic the Gathering cards with mutate appear almost exclusively in the Ikoria MtG set and MtG Commander decks - you can check out our guide to MtG Arena codes if you'd like to pick up some Ikoria cards and experiment with mutate in Historic or Brawl

So much that these three cards are either banned in multiple other formats or rebalanced to be weaker, and Modern is one of the few ways you can play them all together

At the time Timetwister was released, you could play the Mox artifacts, zero mana artifacts that provide mana